Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Preparation of Spirocyclic β-Proline Esters : Geometrically Restricted Building Blocks for Medicinal Chemistry. / Fjelbye, Kasper; Marigo, Mauro; Clausen, Rasmus Prætorius; Juhl, Karsten.

I: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis, Bind 28, Nr. 2, st-2016-b0534-l, 2017, s. 231-234.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Fjelbye, K, Marigo, M, Clausen, RP & Juhl, K 2017, 'Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry', SYNLETT: Accounts and Rapid Communications in Chemical Synthesis, bind 28, nr. 2, st-2016-b0534-l, s. 231-234. https://doi.org/10.1055/s-0036-1588902

APA

Fjelbye, K., Marigo, M., Clausen, R. P., & Juhl, K. (2017). Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry. SYNLETT: Accounts and Rapid Communications in Chemical Synthesis, 28(2), 231-234. [st-2016-b0534-l]. https://doi.org/10.1055/s-0036-1588902

Vancouver

Fjelbye K, Marigo M, Clausen RP, Juhl K. Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry. SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 2017;28(2):231-234. st-2016-b0534-l. https://doi.org/10.1055/s-0036-1588902

Author

Fjelbye, Kasper ; Marigo, Mauro ; Clausen, Rasmus Prætorius ; Juhl, Karsten. / Preparation of Spirocyclic β-Proline Esters : Geometrically Restricted Building Blocks for Medicinal Chemistry. I: SYNLETT: Accounts and Rapid Communications in Chemical Synthesis. 2017 ; Bind 28, Nr. 2. s. 231-234.

Bibtex

@article{de2be03190eb4905a069d432b69ab863,
title = "Preparation of Spirocyclic β-Proline Esters: Geometrically Restricted Building Blocks for Medicinal Chemistry",
abstract = "A series of novel N-Bn-protected spirocyclic β-proline esters were prepared using [3+2] cycloaddition and subsequently converted into their corresponding aldehydes. In addition, two novel N-Cbz-protected spirocyclic β-proline esters were prepared using intramolecular cyclization starting from simple precursors.",
keywords = "1,3-dipolar cycloaddition, intramolecular cyclization, oxetanes, spirocycles, β-proline esters",
author = "Kasper Fjelbye and Mauro Marigo and Clausen, {Rasmus Pr{\ae}torius} and Karsten Juhl",
year = "2017",
doi = "10.1055/s-0036-1588902",
language = "English",
volume = "28",
pages = "231--234",
journal = "SYNLETT: Accounts and Rapid Communications in Chemical Synthesis",
issn = "0936-5214",
publisher = "Thieme",
number = "2",

}

RIS

TY - JOUR

T1 - Preparation of Spirocyclic β-Proline Esters

T2 - Geometrically Restricted Building Blocks for Medicinal Chemistry

AU - Fjelbye, Kasper

AU - Marigo, Mauro

AU - Clausen, Rasmus Prætorius

AU - Juhl, Karsten

PY - 2017

Y1 - 2017

N2 - A series of novel N-Bn-protected spirocyclic β-proline esters were prepared using [3+2] cycloaddition and subsequently converted into their corresponding aldehydes. In addition, two novel N-Cbz-protected spirocyclic β-proline esters were prepared using intramolecular cyclization starting from simple precursors.

AB - A series of novel N-Bn-protected spirocyclic β-proline esters were prepared using [3+2] cycloaddition and subsequently converted into their corresponding aldehydes. In addition, two novel N-Cbz-protected spirocyclic β-proline esters were prepared using intramolecular cyclization starting from simple precursors.

KW - 1,3-dipolar cycloaddition

KW - intramolecular cyclization

KW - oxetanes

KW - spirocycles

KW - β-proline esters

U2 - 10.1055/s-0036-1588902

DO - 10.1055/s-0036-1588902

M3 - Review

AN - SCOPUS:84991735346

VL - 28

SP - 231

EP - 234

JO - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

JF - SYNLETT: Accounts and Rapid Communications in Chemical Synthesis

SN - 0936-5214

IS - 2

M1 - st-2016-b0534-l

ER -

ID: 176009623