Ansatte – Københavns Universitet

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Institut for Lægemiddeldesign og Farmakologi > Ansatte

Jesper Langgaard Kristensen

Jesper Langgaard Kristensen

Lektor

Primære forskningsområder

Research interests

Generally medicinal chemistry and the development of new methodology for the construction of compound classes of relevance to medicinal chemistry. Using these tools we are trying to develop new probes and tools that will help us to elucidate the underlying mechanisms responsible for the regulation of different pharmacological targets: Ion channels, enzymes and GPCR’s.

Please see group web-page for more informantion.

Co-founder of Dep-Xplora

Dep-Xplora is a biotec company developing a novel prodrug principle to deliver NSAIDs into joints.

 

Udvalgte publikationer

  1. Udgivet

    Metabolic fate of hallucinogenic NBOMes

    Leth-Petersen, S., Gabel-Jensen, C., Gillings, N., Lehel, S., Hansen, H. D., Knudsen, G. M. & Kristensen, J. L. 2016 I : Chemical Research in Toxicology. 29, 1, s. 96–100 5 s.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  2. Udgivet

    Evaluation of 3-Ethyl-3-(phenylpiperazinylbutyl)oxindoles as PET Ligands for the Serotonin 5-HT7 Receptor: Synthesis, Pharmacology, Radiolabeling, and in Vivo Brain Imaging in Pigs

    Herth, M. M., Andersen, V. L., Hansen, H. D., Stroth, N., Volk, B., Lehel, S., Dyssegaard, A., Ettrup, A., Svenningsson, P., Knudsen, G. M. & Kristensen, J. L. 13 apr. 2015 I : Journal of medicinal chemistry. 58, 8, s. 3631–3636 16 s.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  3. Udgivet

    Convergent [18]F-labeling and evaluation of N-benzyl-phenethylamines as 5-HT2A receptor PET ligands

    Petersen, I. N., Villadsen, J., Hansen, H. D., Jensen, A. A., Lehel, S., Gillings, N., Herth, M. M., Knudsen, G. M. & Kristensen, J. L. 2016 I : Bioorganic & Medicinal Chemistry. 24, s. 5353-5356 4 s.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  4. Udgivet

    Tying up Nicotine: New Selective Competitive Antagonist of the Neuronal Nicotinic Acetylcholine Receptors

    Petersen, I. N., Crestey, F., Jensen, A. A., Indurthi, D. C., Pedersen, H., Andreasen, J. T., Balle, T. & Kristensen, J. L. 9 apr. 2015 I : A C S Medicinal Chemistry Letters. 6, 4, s. 472-475 4 s.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  5. Udgivet

    Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists

    Hansen, M., Phonekeo, K., Paine, J. S., Leth-Petersen, S., Begtrup, M., Bräuner-Osborne, H. & Kristensen, J. L. 7 jan. 2014 I : A C S Chemical Neuroscience. 5, 3, s. 243-249 8 s.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  6. Udgivet

    Design, synthesis and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists

    Crestey, F., Jensen, A. A., Borch, M., Andreasen T., J., Andersen, J., Balle, T. & Kristensen, J. L. 2013 I : Journal of Medicinal Chemistry. 56, 23, s. 9673-9682

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

ID: 1305029