Effect of amiloride on arachidonic acid and histamine release from rat mast cells
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The effect of a putative Na/H exchange inhibition on histamine and [C]arachidonic acid ([C]AA) release has been examined in rat peritoneal mast cells, using either addition of amiloride or removal of extracellular Na. The cells were stimulated by non-immunological agents, i.e. calcium ionophore A23187, nerve growth factor (NGF), thapsigargin and compound 48/80. On the basis of the results obtained, a possible role for Na/H exchange in rat mast cell secretion is discussed.
Originalsprog | Engelsk |
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Tidsskrift | Agents and Actions |
Vol/bind | 27 |
Udgave nummer | 1-2 |
Sider (fra-til) | 39-42 |
Antal sider | 4 |
ISSN | 0065-4299 |
Status | Udgivet - 1 jan. 1989 |
ID: 45562135