Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Daniel T Barratt
  • Benedikte Bandak
  • Pål Klepstad
  • Ola Dale
  • Stein Kaasa
  • Christrup, Lona Louring
  • Jonathan Tuke
  • Andrew A Somogyi
This study aimed to investigate whether CYP3A4/5 genetic variants, together with clinical and patient factors, influence serum fentanyl and norfentanyl concentrations and their ratio in cancer pain patients receiving transdermal fentanyl.
OriginalsprogEngelsk
TidsskriftPharmacogenetics and Genomics
Vol/bind24
Udgave nummer4
Sider (fra-til)185-194
Antal sider10
ISSN1744-6872
StatusUdgivet - 2014

ID: 101829242