Relative bioavailability in man of noscapine administered in lozenges and mixture
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
The bioavailability of noscapine base administered in lozenges in a dose of 100 mg to twelve healthy volunteers, in a study using an open balanced cross-over design, was compared with that of 100 mg of noscapine hydrochloride given perorally as a mixture. The bioavailability of noscapine after administration in lozenges was significantly higher than that after administration of the drug as a mixture. It is concluded that the lozenges containing noscapine base may be a valuable alternative to the conventional noscapine hydrochloride mixture.
Originalsprog | Engelsk |
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Tidsskrift | Acta Pharmaceutica Nordica |
Vol/bind | 4 |
Udgave nummer | 4 |
Sider (fra-til) | 309-312 |
Antal sider | 4 |
ISSN | 1100-1801 |
Status | Udgivet - 1 jan. 1992 |
ID: 46100967