Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice

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Standard

Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice. / Winding, Bent; NicAmhlaoibh, Róisín; Misander, Henriette; Høegh-Andersen, Pernille; Andersen, Thomas Levin; Holst-Hansen, Claus; Heegaard, Anne-Marie; Foged, Niels Taekker; Brünner, Nils; Delaissé, Jean-Marie.

I: Clinical Cancer Research, Bind 8, Nr. 6, 2002, s. 1932-9.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Winding, B, NicAmhlaoibh, R, Misander, H, Høegh-Andersen, P, Andersen, TL, Holst-Hansen, C, Heegaard, A-M, Foged, NT, Brünner, N & Delaissé, J-M 2002, 'Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice', Clinical Cancer Research, bind 8, nr. 6, s. 1932-9.

APA

Winding, B., NicAmhlaoibh, R., Misander, H., Høegh-Andersen, P., Andersen, T. L., Holst-Hansen, C., Heegaard, A-M., Foged, N. T., Brünner, N., & Delaissé, J-M. (2002). Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice. Clinical Cancer Research, 8(6), 1932-9.

Vancouver

Winding B, NicAmhlaoibh R, Misander H, Høegh-Andersen P, Andersen TL, Holst-Hansen C o.a. Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice. Clinical Cancer Research. 2002;8(6):1932-9.

Author

Winding, Bent ; NicAmhlaoibh, Róisín ; Misander, Henriette ; Høegh-Andersen, Pernille ; Andersen, Thomas Levin ; Holst-Hansen, Claus ; Heegaard, Anne-Marie ; Foged, Niels Taekker ; Brünner, Nils ; Delaissé, Jean-Marie. / Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice. I: Clinical Cancer Research. 2002 ; Bind 8, Nr. 6. s. 1932-9.

Bibtex

@article{ed8f47025e1a4aff813d9cfaba4461d4,
title = "Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice",
abstract = "Breast cancer frequently leads to incurable bone metastasis. Essential requirements for the development of bone metastasis are cell-cell and cell-matrix interactions, release of bioactive growth factors and cytokines, and removal of large amounts of bone matrix. Matrix metalloproteinases (MMPs) play an important role in all of these processes, but the possibility of using synthetic MMP inhibitors to decrease bone metastasis has received little attention.",
keywords = "Animals, Antineoplastic Agents, Bone Neoplasms, Breast Neoplasms, Cell Survival, Dipeptides, Female, Gene Therapy, Humans, Matrix Metalloproteinases, Mice, Mice, Inbred BALB C, Mice, Nude, Neoplasm Invasiveness, Osteolysis, Phenylalanine, Protease Inhibitors, Thiophenes, Transfection, Transplantation, Heterologous, Tumor Cells, Cultured",
author = "Bent Winding and R{\'o}is{\'i}n NicAmhlaoibh and Henriette Misander and Pernille H{\o}egh-Andersen and Andersen, {Thomas Levin} and Claus Holst-Hansen and Anne-Marie Heegaard and Foged, {Niels Taekker} and Nils Br{\"u}nner and Jean-Marie Delaiss{\'e}",
year = "2002",
language = "English",
volume = "8",
pages = "1932--9",
journal = "Clinical Cancer Research",
issn = "1078-0432",
publisher = "American Association for Cancer Research (A A C R)",
number = "6",

}

RIS

TY - JOUR

T1 - Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice

AU - Winding, Bent

AU - NicAmhlaoibh, Róisín

AU - Misander, Henriette

AU - Høegh-Andersen, Pernille

AU - Andersen, Thomas Levin

AU - Holst-Hansen, Claus

AU - Heegaard, Anne-Marie

AU - Foged, Niels Taekker

AU - Brünner, Nils

AU - Delaissé, Jean-Marie

PY - 2002

Y1 - 2002

N2 - Breast cancer frequently leads to incurable bone metastasis. Essential requirements for the development of bone metastasis are cell-cell and cell-matrix interactions, release of bioactive growth factors and cytokines, and removal of large amounts of bone matrix. Matrix metalloproteinases (MMPs) play an important role in all of these processes, but the possibility of using synthetic MMP inhibitors to decrease bone metastasis has received little attention.

AB - Breast cancer frequently leads to incurable bone metastasis. Essential requirements for the development of bone metastasis are cell-cell and cell-matrix interactions, release of bioactive growth factors and cytokines, and removal of large amounts of bone matrix. Matrix metalloproteinases (MMPs) play an important role in all of these processes, but the possibility of using synthetic MMP inhibitors to decrease bone metastasis has received little attention.

KW - Animals

KW - Antineoplastic Agents

KW - Bone Neoplasms

KW - Breast Neoplasms

KW - Cell Survival

KW - Dipeptides

KW - Female

KW - Gene Therapy

KW - Humans

KW - Matrix Metalloproteinases

KW - Mice

KW - Mice, Inbred BALB C

KW - Mice, Nude

KW - Neoplasm Invasiveness

KW - Osteolysis

KW - Phenylalanine

KW - Protease Inhibitors

KW - Thiophenes

KW - Transfection

KW - Transplantation, Heterologous

KW - Tumor Cells, Cultured

M3 - Journal article

C2 - 12060638

VL - 8

SP - 1932

EP - 1939

JO - Clinical Cancer Research

JF - Clinical Cancer Research

SN - 1078-0432

IS - 6

ER -

ID: 38426485