Invited Lecture: From Host Defence Peptides to New Antibiotics
Publikation: Konferencebidrag › Konferenceabstrakt til konference › Forskning
Antimicrobial peptides hold promise as the next generation of antimicrobial agents. However, the potential is weakened by their susceptibility to proteolytic degradation, poor bioavailabillity , toxicity and high cost. Our research interest is in determining the structure/activity relationships of these antimicrobial peptides, which enables us to better understand their mechanism of action and facilitates the development of lead antimicrobial agents. As an example, in this talk I will focus on our work on anoplin and analogues, a decapeptide isolated from the Japanese wasp Anoplius samariensis. I will describe the elucidation of their structure/activity relationships, and our efforts towards developing them into antibiotics.
Originalsprog | Engelsk |
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Publikationsdato | 2014 |
Status | Udgivet - 2014 |
Begivenhed | Antibiotic alternatives for the new millennium - London, London, Storbritannien Varighed: 5 nov. 2014 → 7 nov. 2014 |
Konference
Konference | Antibiotic alternatives for the new millennium |
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Lokation | London |
Land | Storbritannien |
By | London |
Periode | 05/11/2014 → 07/11/2014 |
ID: 127141479