Aliphatic 18F-Radiofluorination: Recent Advances in the Labeling of Base-Sensitive Substrates**
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Aliphatic fluorine-18 radiolabeling is the most commonly used method to synthesize tracers for PET-imaging. With an increasing demand for 18F-radiotracers for clinical applications, new labeling strategies aiming to increase radiochemical yields of established tracers or, more importantly, to enable 18F-labeling of new scaffolds have been developed. In recent years, increased attention has been focused on the direct aliphatic 18F-fluorination of base-sensitive substrates in this respect. This minireview gives a concise overview of the recent advances within this field and aims to highlight the advantages and limitations of these methods.
Originalsprog | Engelsk |
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Tidsskrift | ChemMedChem |
Vol/bind | 16 |
Udgave nummer | 17 |
Sider (fra-til) | 2612-2622 |
ISSN | 1860-7179 |
DOI | |
Status | Udgivet - 2021 |
Bibliografisk note
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© 2021 Wiley-VCH GmbH
ID: 281708809