Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides

Publikation: Bidrag til tidsskriftTidsskriftartikelForskningfagfællebedømt

  • Joseph I Ambrus
  • Jill I Halliday
  • Nicholas Kanizaj
  • Nathan Absalom
  • Harpsøe, Kasper
  • Thomas Balle
  • Mary Chebib
  • Malcolm D McLeod
The 3-methylmaleimide congeners of the natural product methyllycaconitine (MLA) and an analogue covalently attach to functional cysteine mutants of the a7 nicotinic acetylcholine receptor (nAChR).
OriginalsprogEngelsk
TidsskriftChemical Communications
Vol/bind48
Udgave nummer53
Sider (fra-til)6699-6701
Antal sider3
ISSN1359-7345
DOI
StatusUdgivet - 7 jul. 2012

ID: 38251255