Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa
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Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa. / Schmidt, Marianne Molander; Nielsen, Line Hagner; Søgaard, Søren Vinter; Stærk, Dan; Rønsted, Nina; Diallo, Drissa; Kusamba Zacharie, Chifundera; van Staden, Johannes; Jäger, Anna.
I: Journal of Ethnopharmacology, Bind 157, 2014, s. 171-180.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Hyaluronidase, phospholipase A2 and protease inhibitory activity of plants used in traditional treatment of snakebite-induced tissue necrosis in Mali, DR Congo and South Africa
AU - Schmidt, Marianne Molander
AU - Nielsen, Line Hagner
AU - Søgaard, Søren Vinter
AU - Stærk, Dan
AU - Rønsted, Nina
AU - Diallo, Drissa
AU - Kusamba Zacharie, Chifundera
AU - van Staden, Johannes
AU - Jäger, Anna
PY - 2014
Y1 - 2014
N2 - ETHNOPHARMACOLOGICAL RELEVANCE:Snakebite envenomation, every year, causes estimated 5-10,000 mortalities and results in more than 5-15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional medicine systems contain compounds against the necrosis-inducing enzymes of snake venom.
AB - ETHNOPHARMACOLOGICAL RELEVANCE:Snakebite envenomation, every year, causes estimated 5-10,000 mortalities and results in more than 5-15,000 amputations in sub-Saharan Africa alone. Antiserum is not easily accessible in these regions or doctors are simply not available, thus more than 80% of all patients seek traditional practitioners as first-choice. Therefore it is important to investigate whether the plants used in traditional medicine systems contain compounds against the necrosis-inducing enzymes of snake venom.
U2 - 10.1016/j.jep.2014.09.027
DO - 10.1016/j.jep.2014.09.027
M3 - Journal article
C2 - 25256691
VL - 157
SP - 171
EP - 180
JO - Journal of Ethnopharmacology
JF - Journal of Ethnopharmacology
SN - 0378-8741
ER -
ID: 123611306