NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
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NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.). / Broholm, Sofie L.; Gramsbergen, Simone; Nyberg, Nils; Jäger, Anna; Stærk, Dan.
2015. Poster session præsenteret ved 36th Danish NMR Meeting, Lund, Sverige.Publikation: Konferencebidrag › Poster › Forskning
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TY - CONF
T1 - NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
AU - Broholm, Sofie L.
AU - Gramsbergen, Simone
AU - Nyberg, Nils
AU - Jäger, Anna
AU - Stærk, Dan
PY - 2015
Y1 - 2015
N2 - Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to controlpostprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of thisproject is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
AB - Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to controlpostprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of thisproject is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
M3 - Poster
T2 - 36th Danish NMR Meeting
Y2 - 19 January 2015 through 20 January 2015
ER -
ID: 130334039