Synthesis of peptides using tert-butyloxycarbonyl (Boc) as the α-amino protection group
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning
The use of the tert-butyloxycarbonyl (Boc) as the Nα-amino protecting group in peptide synthesis can be advantageous in several cases, such as synthesis of hydrophobic peptides and peptides containing ester and thioester moieties. The primary challenge of using Boc SPPS is the need for treatment of the resin-bound peptide with hazardous hydrogen fluoride (HF), which requires special equipment.
Originalsprog | Engelsk |
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Titel | Peptide synthesis and applications |
Antal sider | 16 |
Vol/bind | 1047 |
Forlag | Humana Press |
Publikationsdato | 2013 |
Sider | 65-80 |
ISBN (Elektronisk) | 978-1-62703-544-6 |
DOI | |
Status | Udgivet - 2013 |
Navn | Methods in Molecular Biology |
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ISSN | 1064-3745 |
ID: 100049878